Methods, Statistics and Programming Working Group

VAC4EU conducts primarily real-world evidence (RWE) studies. In other words, electronic healthcare data from various sources is re-used for the purpose of answering a research question. First, the Data Expert & Access Partners (DEAPs) extract the data and load it to a Common Data Model (CDM). Then, statisticians and programmers use R software to develop central analytical scripts to run against the CDM and generate estimates tailored to answering the research question(s) of the study.

The MSP WG exists as a shared space for statisticians, methodologists or programmers to exchange tools, knowledge, and relevant information across different studies. These include logistical matters, such as developing guidelines and standard operating procedures, but also methodological issues. For example, a taskforce was formed to evaluate the best approach to generate synthetic data for central programming development and testing.

Taskforces (TF) 

• Programming Guidelines TF
• Code List TF
• Synthetic Data TF
• Self-Controlled Risk Intervals TF