ADVANCE output
Accelerated Development of VAccine beNefit-risk Collaboration in Europe (ADVANCE) was an IMI project established in 2013 as a response to the 2009 H1N1 pandemic (also known as swine flu)
As funding from the Innovative Medicines Initiative ended at the close of the project, the project partners decided to sustain this work through a non-profit organisation. This is how VAC4EU was established. You can learn more about that following link below.
Impact
Aside from the establishment of VAC4EU as a follow up, ADVANCE had many outputs and many lessons to share with the world. We invite you to browse through these with the links aside!
Outputs
Throughout its duration, ADVANCE generated a wealth of knowledge and practical tools for vaccine benefit-risk assessment. Explore the project’s outputs below to discover its publications, deliverables, webinars, and other materials that continue to inform evidence-based vaccine monitoring today.
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List of study needs and framework requirements draft R Month 61.01
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List of topics for proof-of-concept studies Ph I R Month 61.02
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Final report on existing models of public-private interactions R Month 91.03
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Analysis of public concerns and perceptions related to benefits and risks of vaccines R Month 121.04
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Initial conceptual model for public-private interaction R Month 151.05
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Guidance on best practices draft P Month 181.06
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Analysis of key issues and gaps about perception and knowledge on benefits and risks of vaccines R Month 241.07
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List of topics for proof-of-concept studies Ph II R Month 281.08
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Final conceptual model for public-private interaction R Month 361.1
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List of study needs and framework requirements final R Month 361.11
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Strategy for public communication in the context of vaccine benefit-risk monitoring P Month 361.12
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White paper (recommendations) of WP1 for the final Blueprint (WP7)1.13
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Report on landscape of existing initiatives and potential synergies2.01
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Utilization strategy of outputs from other initiatives2.02
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Interim report on synergy and collaboration with other initiatives2.03
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Final report on landscape analysis, synergies, added value of ADVANCE and future opportunities2.04
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First report on the technical requirements analysis3.01
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First report on data access linkage and integration for POC studies3.02
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Final report on the technical requirements analysis3.03
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Catalogue and meta profiles of data sources for vaccine benefit-risk monitoring3.04
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White paper regarding procedures for data access, sharing, linkage and integration, including privacy and ethics3.05
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"Report on tested methods for burden of disease, vaccine coverage, vaccine effectiveness "4.04
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Report on tested methods for vaccine safety4.05
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"Report on tested methods for assessing the benefit-risk of vaccines "4.06
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"Report on text mining approaches to accelerate development of case definitions and automated case validation from medical records"4.07
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Report on utilities for benefit-risk monitoring4.08
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4"White paper (recommendations) of WP4 for the final Blueprint (WP7) "09
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Report on available IT Platform5.01
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Research plan for PC & MOC studies5.03
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Report on disease ontologies and codes5.05
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Results of Mock-up/ POC studies Phase 15.06
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Results of Mock-up/ POC studies Phase 25.07
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Report on stakeholder feedback5.08
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"White paper (recommendations) of WP5 for the final Blueprint (WP7) "5.09
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"Public website and tools for internal collaboration and communication"6.01
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Project handbook6.02
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Project communication plan and initial tool set6.03
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Annual technical and financial reports #16.04
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Annual technical and financial reports #26.05
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Project assessment6.06
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Annual technical and financial reports #36.07
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Annual technical and financial reports #46.08
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"Report on activities implemented supporting internal communication, knowledge management and training"6.09
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Report on dissemination activities6.1
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Annual technical and financial reports #56.11
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Compilation from WP7 of recommendations made during the year on key deliverables no.17.01
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"Compilation from WP7 of recommendations made during the year on key deliverables no.2"7.02
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"Compilation from WP7 of recommendations made during the year on key deliverables no.3"7.03
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"Compilation from WP7 of recommendations made during the year on key deliverables no.4"7.04
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Draft Blueprint for public consultation7.05
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Summary report of public consultation7.06
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Final blueprint7.07
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Conference "EU ecosystem for monitoring of post-licensure vaccine benefit and risk: From ADVANCE to VAC4EU"6 March 2019
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Interactive dashboard to monitor vaccine benefit and risk