Results
Methods
Estimation of coverage, effectiveness, risks and benefit-risk of vaccines using heterogeneous health care databases in Europe, requires continuous innovation of methods. The consortium has created reports on the state of the art methods and has developed several new methodologies.
Publications:
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De Smedt et al. Bias due to differential and non-differential disease- and exposure misclassification in studies of vaccine effectiveness. |
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McDonald et al. Methodology for computing the burden of disease of adverse events following immunization. |
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Dodd CN et al. ADVANCE system testing estimating the incidence of adverse events with incomplete information on exposure. |
Reports:
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ADVANCE results: Report on tested novel methods |
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ADVANCE results: White paper – methods for vaccine benefit-risk monitoring |
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ADVANCE results: Appraisal of vaccine safety assessment methods |
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ADVANCE: Appraisal of coverage and benefit assessment methods |
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ADVANCE results: Appraisal of Benefit-risk assessment methods |